| 2008 Division II Baseball All-Region Team | |||
| Player | Pos. | School | |
| First Team | |||
| Matthew McGovern | P | Monroe Community College | |
| Steve Forster | P | Monroe Community College | |
| Cory Brownsten | C | Monroe Community College | |
| Kevin Underhill | IF | Alfred State College | |
| Kaleb Cunningham | IF | Monroe Community College | |
| Steve Muoio | IF | Monroe Community College | |
| Dan Kaplan | IF | Monroe Community College | |
| Yorman Romero | IF | Mercyhurst North East College | |
| Derek Speaker | OF | Alfred State College | |
| Nate Grabowski | OF | Monroe Community College | |
| Bruno Saraceno | OF | Alfred State College | |
| Carlos Zuniga | DH | Mercyhurst North East | |
|
Second Team |
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| Andrew Foster | P | Alfred State College | |
| Craig Kosnikowski | P | Alfred State College | |
| Mike Jackson | P | Mercyhurst North East | |
| Kelvin Espinosa | C | Alfred State College | |
| Adalberto Vargas | IF | Alfred State College | |
| Yordis Veras | IF | Alfred State College | |
| Jeff Osler | OF | Monroe Community College | |
| Jamie Fitzgerald | DH | Monroe Community College | |