| 2010 Men's Lacrosse All-Region Team | |||
| Player | Pos. | School | |
| First Team | |||
| Heather Ziccarelli | Monroe Community College | ||
| Danielle Luduca | Monroe Community College | ||
| Lexi Crusha | Monroe Community College | ||
| Kaila Fox | Monroe Community College | ||
| Lauren Welch | Onondaga Community College | ||
| Emily Pierson | Onondaga Community College | ||
| Amanda Cizenski | Onondaga Community College | ||
| Elizabeth Manipole | Onondaga Community College | ||
| Nicole Greco | Onondaga Community College | ||
| Alisha Brooks | Cayuga Community College | ||
| Lauren Prescetti | Herkimer County Community College | ||
| Brittany Hohwald | Herkimer County Community College | ||
| Betheny Jennings | Herkimer County Community College | ||
| Tara Gervera | Jefferson Community College | ||
| Kasey Kuzma | Broome Community College | ||
| Laura Nerber | Erie Community College | ||
| Sarah Lirchberger | Erie Community College | ||
| Kelsey McKeown | Erie Community College | ||
|
Second Team |
|||
| Brittany Clause | Onondaga Community College | ||
| Jamie Handley | Onondaga Community College | ||
| Maggie Doerle | Onondaga Community College | ||
| Caitlyn Kumkey | Monroe Community College | ||
| Mara Mason | Monroe Community College | ||
| Allyn Parrino | Monroe Community College | ||
| Kayley Oddo | Niagara County Community College | ||
| Laura Iwanicki | Cayuga Community College | ||
| Kim Vrigian | Herkimer County Community College | ||
| Sarah Doroze | Herkimer County Community College | ||
| Danielle Shockley | Jefferson Community College | ||
| Nicole Perry | Jefferson Community College | ||
| Brittney Riveras | Broome Community College | ||
| Katie Fairbrother | Broome Community College | ||
| Jessica Flowers | Erie Community College | ||
| Alyssa Ashcroft | Erie Community College | ||
|
Player of the Year |
|||
| Emily Pierson | Onondaga Community College | ||
|
Coach of the Year |
|||
| Diane Ste-Marie | Herkimer County Community College | ||